Secretory IgA Serve as Receptors for Ricin Oligosaccharide Side Chains on Human
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منابع مشابه
Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication.
Epithelial cells of the respiratory and gastrointestinal tracts are extremely vulnerable to the cytotoxic effects of ricin, a Shiga-like toxin with ribosome-inactivating properties. While mucosal immunity to ricin correlates with secretory immunoglobulin A (IgA) antibody levels in vivo, the potential of IgA to protect epithelial cells from ricin in vitro has not been examined due to the unavail...
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